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Truth Classification

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Capsule of the Day

DebunkedThe PolygraphThe instrument popularly called a lie detector, which records breathing, blood pressure, pulse and skin conductance dur…

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The library

Capsules

1,028 capsules, each one classified by the strength of its evidence.

All1,028 Fact599 Proven130 Theory89 Hypothesis71 Contested90 Debunked48

geography236 biology88 physics67 history54 medicine45 astronomy33 psychology26 mathematics26 chemistry20 engineering20 astrophysics19 neuroscience19 anthropology18 art18

Filtered byHypothesis medicine medicine Clear all

Results

Showing 1 to 11 of 11

Newest Most voted A to Z

Developmental Origins of Health and Disease

The proposal that conditions in the womb and in early infancy set a person's risk of heart disease, diabetes and other conditions decades later. It…

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The Glutamate Hypothesis of Schizophrenia

The proposal that schizophrenia involves underactive NMDA receptors rather than, or as well as, excess dopamine. It explains what the dopamine…

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The Seed and Soil Hypothesis

The proposal that cancers spread to particular organs not by accident of circulation but because those tissues are hospitable to them. It was…

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The Warburg Effect

Cancer cells burn glucose wastefully, converting it to lactate even when oxygen is plentiful. The observation is a century old and undisputed, it is…

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The Inflammatory Hypothesis of Depression

The proposal that inflammation causes depression in some patients. The evidence is better than for the serotonin account it partly replaced, and the…

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The Social Defeat Hypothesis of Psychosis

The proposal that chronic experience of being excluded or subordinated raises the risk of psychosis, by sensitising the brain's dopamine system. It…

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The Cancer Stem Cell Hypothesis

The proposal that tumours are sustained by a small subpopulation of cells with stem-like properties, and that killing the bulk of a tumour without…

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The Gut-Brain Axis

The proposal that gut microbes influence mood, behaviour and neurological disease, and that altering them could treat psychiatric and…

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The Dopamine Hypothesis of Schizophrenia

The proposal that psychosis results from excess dopamine signalling. It has organised psychiatry for sixty years, it was inferred backwards from…

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The Serotonin Hypothesis of Depression

The proposal that depression is caused by low serotonin, and that antidepressants work by correcting it. The popular version of this claim is not…

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The Amyloid Hypothesis

The proposal that Alzheimer's disease is caused by the accumulation of amyloid beta protein in the brain. It has directed the field for over thirty…

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