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DebunkedThe PolygraphThe instrument popularly called a lie detector, which records breathing, blood pressure, pulse and skin conductance dur…

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The library

Capsules

1,028 capsules, each one classified by the strength of its evidence.

All1,028Fact599Proven130Theory89Hypothesis71Contested90Debunked48
geography236biology88physics67history54medicine45astronomy33psychology26mathematics26chemistry20engineering20astrophysics19neuroscience19anthropology18art18
Filtered byHypothesisneuroscienceClear all

Results

Showing 1 to 10 of 10

NewestMost votedA to Z
medicine
Hypothesis

The Glutamate Hypothesis of Schizophrenia

The proposal that schizophrenia involves underactive NMDA receptors rather than, or as well as, excess dopamine. It explains what the dopamine…

byCapsule
0 votes0 reviews
neuroscience
Hypothesis

Integrated Information Theory

Giulio Tononi's proposal that consciousness is integrated information, quantifiable as a number called phi, and present wherever that number is above…

byCapsule0 votes0 reviews
neuroscience
Hypothesis

The Free Energy Principle

Karl Friston's proposal that everything a brain does, and arguably everything any self-organising system does, can be described as minimising a…

byCapsule0 votes0 reviews
neuroscience
Hypothesis

The Glymphatic System

The proposal that the brain flushes waste through a network of fluid-filled channels, and that the flushing happens mainly during sleep. It was…

byCapsule0 votes0 reviews
medicine
Hypothesis

The Gut-Brain Axis

The proposal that gut microbes influence mood, behaviour and neurological disease, and that altering them could treat psychiatric and…

byCapsule0 votes0 reviews
medicine
Hypothesis

The Dopamine Hypothesis of Schizophrenia

The proposal that psychosis results from excess dopamine signalling. It has organised psychiatry for sixty years, it was inferred backwards from…

byCapsule0 votes0 reviews
medicine
Hypothesis

The Serotonin Hypothesis of Depression

The proposal that depression is caused by low serotonin, and that antidepressants work by correcting it. The popular version of this claim is not…

byCapsule0 votes0 reviews
medicine
Hypothesis

The Amyloid Hypothesis

The proposal that Alzheimer's disease is caused by the accumulation of amyloid beta protein in the brain. It has directed the field for over thirty…

byCapsule0 votes0 reviews
anthropology
Hypothesis

The Social Brain Hypothesis

The proposal that primate brains grew large to manage social relationships rather than to solve ecological problems, and that the size of a species'…

byCapsule0 votes0 reviews
science
Hypothesis

Quantum Entanglement as a Substrate for Consciousness

The hypothesis proposes that quantum entanglement between microtubule subunits inside neurons could provide a physical substrate for unified…

byCapsule0 votes0 reviews