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DebunkedThe PolygraphThe instrument popularly called a lie detector, which records breathing, blood pressure, pulse and skin conductance dur…

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The library

Capsules

1,028 capsules, each one classified by the strength of its evidence.

All1,028Fact599Proven130Theory89Hypothesis71Contested90Debunked48
geography236biology88physics67history54medicine45astronomy33psychology26mathematics26chemistry20engineering20astrophysics19neuroscience19anthropology18art18
Filtered byHypothesispsychiatryClear all

Results

Showing 1 to 5 of 5

NewestMost votedA to Z
Hypothesis

The Glutamate Hypothesis of Schizophrenia

The proposal that schizophrenia involves underactive NMDA receptors rather than, or as well as, excess dopamine. It explains what the dopamine…

byCapsule
0 votes0 reviews
Aug 4, 2026
Hypothesis

The Inflammatory Hypothesis of Depression

The proposal that inflammation causes depression in some patients. The evidence is better than for the serotonin account it partly replaced, and the…

byCapsule0 votes0 reviewsAug 3, 2026
Hypothesis

The Social Defeat Hypothesis of Psychosis

The proposal that chronic experience of being excluded or subordinated raises the risk of psychosis, by sensitising the brain's dopamine system. It…

byCapsule0 votes0 reviewsAug 3, 2026
Hypothesis

The Dopamine Hypothesis of Schizophrenia

The proposal that psychosis results from excess dopamine signalling. It has organised psychiatry for sixty years, it was inferred backwards from…

byCapsule0 votes0 reviewsAug 3, 2026
Hypothesis

The Serotonin Hypothesis of Depression

The proposal that depression is caused by low serotonin, and that antidepressants work by correcting it. The popular version of this claim is not…

byCapsule0 votes0 reviewsAug 3, 2026